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A simple method for gene phasing using mate pair sequencing

BACKGROUND: Recessive genes cause disease when both copies are affected by mutant loci. Resolving the cis/trans relationship of variations has been an important problem both for researchers, and increasingly, clinicians. Of particular concern are patients who have two heterozygous disease-causing mu...

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מידע ביבליוגרפי
Main Authors: Cradic, Kendall W, Murphy, Stephen J, Drucker, Travis M, Sikkink, Robert A, Eberhardt, Norman L, Neuhauser, Claudia, Vasmatzis, George, Grebe, Stefan KG
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930533/
https://ncbi.nlm.nih.gov/pubmed/24502676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-15-19
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