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A model for hydration of peptides and its application to the conformational analysis of terminally blocked amino acids and dipeptides

A theoretical model for peptide structure, which takes into account the effects of hydration in conformational energy calculations, is described. The free energy of hydration is composed of a term for “specific hydration,” representing solute-water hydrogen bonding, and a term for “non-specific hydr...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Némethy, George, Hodes, Zachary I., Scheraga, Harold A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5760
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