Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI) screens can provide insights into the biological...

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Bibliografski detalji
Glavni autori: Babu, Mohan, Arnold, Roland, Bundalovic-Torma, Cedoljub, Gagarinova, Alla, Wong, Keith S., Kumar, Ashwani, Stewart, Geordie, Samanfar, Bahram, Aoki, Hiroyuki, Wagih, Omar, Vlasblom, James, Phanse, Sadhna, Lad, Krunal, Yeou Hsiung Yu, Angela, Graham, Christopher, Jin, Ke, Brown, Eric, Golshani, Ashkan, Kim, Philip, Moreno-Hagelsieb, Gabriel, Greenblatt, Jack, Houry, Walid A., Parkinson, John, Emili, Andrew
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930520/
https://ncbi.nlm.nih.gov/pubmed/24586182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004120
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