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Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI) screens can provide insights into the biological...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Babu, Mohan, Arnold, Roland, Bundalovic-Torma, Cedoljub, Gagarinova, Alla, Wong, Keith S., Kumar, Ashwani, Stewart, Geordie, Samanfar, Bahram, Aoki, Hiroyuki, Wagih, Omar, Vlasblom, James, Phanse, Sadhna, Lad, Krunal, Yeou Hsiung Yu, Angela, Graham, Christopher, Jin, Ke, Brown, Eric, Golshani, Ashkan, Kim, Philip, Moreno-Hagelsieb, Gabriel, Greenblatt, Jack, Houry, Walid A., Parkinson, John, Emili, Andrew
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930520/
https://ncbi.nlm.nih.gov/pubmed/24586182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004120
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