Inhibition of MAPK-mediated ACE expression by compound C66 prevents STZ-induced diabetic nephropathy

A range of in vitro, experimental and clinical intervention studies have implicated an important role for hyperglycaemia-induced activation of the renin-angiotensin system (RAS) in the development and progression of diabetic nephropathy (DN). Blockade of RAS by angiotensin converting enzyme (ACE) in...

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Detalhes bibliográficos
Main Authors: Pan, Yong, Huang, Yi, Wang, Zhe, Fang, Qilu, Sun, Yusheng, Tong, Chao, Peng, Kesong, Wang, Yangwei, Miao, Lining, Cai, Lu, Zhao, Yunjie, Liang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930410/
https://ncbi.nlm.nih.gov/pubmed/24330074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12175
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