Development and validation of RP-HPLC method with ultraviolet detection for estimation of montelukast in rabbit plasma: Application to preclinical pharmacokinetics

OBJECTIVE: To develop a liquid–liquid extraction based reverse phase liquid chromatography method for estimation of montelukast in rabbit plasma. METHODS: Chromatographic separation was carried out using Phenomenex Luna C18 column (250 mm × 4.6 mm × 5 μm) with mobile phase composed of ammonium aceta...

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Detalhes bibliográficos
Main Authors: Ranjan, Om Prakash, Nayak, Usha Y., Reddy, Meka Sreenivasa, Dengale, Swapnil J., Musmade, Prashant B., Udupa, Nayanabhirama
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930116/
https://ncbi.nlm.nih.gov/pubmed/24563591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jyp.2013.10.006
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