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The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction

The human SLC6 family is composed of approximately 20 structurally related symporters (co-transporters) that use the transmembrane electrochemical gradient to actively import their substrates into cells. Approximately half of the substrates of these transporters are amino acids, with others transpor...

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Detalhes bibliográficos
Main Authors: Rudnick, Gary, Krämer, Reinhard, Blakely, Randy D., Murphy, Dennis L., Verrey, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930102/
https://ncbi.nlm.nih.gov/pubmed/24337881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-013-1410-1
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