Serum stimulates the Na+,K+ pump in quiescent fibroblasts by increasing Na+ entry.
Two ionophores (monensin and gramicidin) that carry Na+ into 3T3 cells markedly enhance the rate of 86Rb+ uptake. Ouabain prevents both ionophores from increasing 86Rb+ uptake, indicating that the ionophores activate the Na+,K+ pump. Measurements of 86Rb+ uptake and cell Na+ and K+ over a range of m...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1978
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/82969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.11.5560 |
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