Development of a Novel Cysteine Sulfinic Acid Decarboxylase Knockout Mouse: Dietary Taurine Reduces Neonatal Mortality

We engineered a CSAD KO mouse to investigate the physiological roles of taurine. The disruption of the CSAD gene was verified by Southern, Northern, and Western blotting. HPLC indicated an 83% decrease of taurine concentration in the plasma of CSAD(−/−). Although CSAD(−/−) generation (G)1 and G2 sur...

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Detalhes bibliográficos
Main Authors: Park, Eunkyue, Park, Seung Yong, Dobkin, Carl, Schuller-Levis, Georgia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929995/
https://ncbi.nlm.nih.gov/pubmed/24639894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/346809
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