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Oral-aboral axis specification in the sea urchin embryo IV. Hypoxia radializes embryos by preventing the initial spatialization of nodal activity

The oral-aboral axis of the sea urchin embryo is specified conditionally via a regulated feedback circuit involving the signaling gene nodal and its antagonist lefty. In normal development nodal activity becomes localized to the prospective oral side of the blastula stage embryo, a process that requ...

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Autors principals: Coffman, James A., Wessels, Abigail, DeSchiffart, Carolyn, Rydlizky, Katarina
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929957/
https://ncbi.nlm.nih.gov/pubmed/24384388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.12.035
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