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High-dose albumin treatment for acute ischaemic stroke (ALIAS): a phase 3, randomised, double-blind, placebo-controlled trial

BACKGROUND: In animal models of ischaemic stroke, 25% albumin reduced brain infarction and improved neurobehavioral outcome. In a pilot clinical trial, albumin doses as high as 2 g per kg were safely tolerated. TRIAL DESIGN AND METHODS: This was a randomised, parallel-group, double-blind trial to te...

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Bibliografiske detaljer
Main Authors: Ginsberg, Myron D., Palesch, Yuko Y., Hill, Michael D., Martin, Renee H., Moy, Claudia S., Barsan, William G., Waldman, Bonnie D., Tamariz, Diego, Ryckborst, Karla J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929943/
https://ncbi.nlm.nih.gov/pubmed/24076337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(13)70223-0
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