Intratumoural budding (ITB) in preoperative biopsies predicts the presence of lymph node and distant metastases in colon and rectal cancer patients

BACKGROUND: In colorectal cancer (CRC), tumour budding at the invasion front is associated with lymph node (LN) and distant metastasis. Interestingly, tumour budding can also be detected in biopsies (intratumoural budding; ITB) and may have similar clinical importance. Here we investigate whether IT...

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Detalhes bibliográficos
Main Authors: Zlobec, I, Hädrich, M, Dawson, H, Koelzer, V H, Borner, M, Mallaev, M, Schnüriger, B, Inderbitzin, D, Lugli, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929877/
https://ncbi.nlm.nih.gov/pubmed/24366305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.797
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