Synthetic LPETG-Containing Peptide Incorporation in the Staphylococcus aureus Cell-Wall in a Sortase A- and Growth Phase-Dependent Manner

The majority of Staphylococcus aureus virulence- and colonization-associated surface proteins contain a pentapeptide recognition motif (LPXTG). This motif can be recognized and cleaved by sortase A (SrtA) which is a membrane-bound transpeptidase. After cleavage these proteins are covalently incorpor...

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Main Authors: Hansenová Maňásková, Silvie, Nazmi, Kamran, van Belkum, Alex, Bikker, Floris J., van Wamel, Willem J. B., Veerman, Enno C. I.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929722/
https://ncbi.nlm.nih.gov/pubmed/24586638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089260
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