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Sodium pyrophosphate inhibition of RNA.DNA hybrid degradation by reverse transcriptase.

Sodium pyrophosphate inhibits synthesis of anticomplementary DNA during a reverse transcriptase (RNA-directed DNA nucleotidyltransferase, EC 2.7.7.7) catalyzed reaction. In the presence of pyrophosphate, the complementary DNA remains stably complexed to the RNA template. In the absence of pyrophosph...

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Bibliographic Details
Main Authors: Myers, J C, Spiegelman, S
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC392956/
https://ncbi.nlm.nih.gov/pubmed/82966
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