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Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells

Purpose. TRPV1 is a multimodal channel mainly expressed in sensory neurons. We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific anta...

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Autors principals: Alvarez-Berdugo, Daniel, Jiménez, Marcel, Clavé, Pere, Rofes, Laia
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929291/
https://ncbi.nlm.nih.gov/pubmed/24688365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/184526
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