High Glucose Modulates Antiproliferative Effect and Cytotoxicity of 5-Fluorouracil in Human Colon Cancer Cells

5-Fluorouracil (5-FU)-based chemotherapy is widely used for the treatment of colorectal cancer (CRC). While optimal doses of 5-FU are generally established based on a patient's estimated body surface area, the plasma concentrations of 5-FU vary among patients. In addition, hyperglycemia in pati...

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Detalhes bibliográficos
Main Authors: Ma, Yi-Shing, Yang, I-Ping, Tsai, Hsiang-Lin, Huang, Ching-Wen, Juo, Suh-Hang Hank, Wang, Jaw-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Research ArticlesOrganelles/Autophagy/Apoptosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929122/
https://ncbi.nlm.nih.gov/pubmed/24283362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2013.2161
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