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Neurocytotoxic antibodies in serum of patients with systemic lupus erythematosus

Sera from patients with systemic lupus erythematosus (SLE) have been tested for antibody to a human neuronal cell line, SK-N-SH, derived from a metastatic neuroblastoma. With a complement-dependent (51)Cr-release cytotoxicity assay, 75% of SLE sera had antineuronal activity mediated by IgM antibody....

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteur principal: Bluestein, Harry G.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1978
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392910/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/279013/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.8.3965
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