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Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders
The molecular basis for the majority of cases of autism spectrum disorders (ASD) remains unknown. We tested the hypothesis that ASD have an epigenetic cause by performing DNA methylation profiling of five CpG islands (CGI-1 to CGI-5) in the SHANK3 gene in postmortem brain tissues from 54 ASD patient...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Oxford University Press
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929093/ https://ncbi.nlm.nih.gov/pubmed/24186872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt547 |
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