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Incoherent Feedforward Control Governs Adaptation of Activated Ras in a Eukaryotic Chemotaxis Pathway

Adaptation in signaling systems, during which the output returns to a fixed baseline after a change in the input, often involves negative feedback loops and plays a crucial role in eukaryotic chemotaxis. We determined the dynamical response to a uniform change in chemoattractant concentration of a e...

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Detalhes bibliográficos
Main Authors: Takeda, Kosuke, Shao, Danying, Adler, Micha, Charest, Pascale G., Loomis, William F., Levine, Herbert, Groisman, Alex, Rappel, Wouter-Jan, Firtel, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928814/
https://ncbi.nlm.nih.gov/pubmed/22215733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002413
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