3-Hydroxy-3-methylglutaryl coenzyme A reductase: regulation of enzymatic activity by phosphorylation and dephosphorylation.

The activity of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) [mevalonate:NADP+ oxidoreductase (CoA-acylating); EC 1.1.1.34] was inhibited by ATP+Mg2+. Inactivation of HMG-CoA reductase by ATP+Mg2+ was dependent on time, temperature, and ATP concentration. Incubation...

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Bibliographic Details
Main Authors: Beg, Z H, Stonik, J A, Brewer, H B
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC392849/
https://ncbi.nlm.nih.gov/pubmed/278983
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