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PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan

Interactions between commensals and the host impact the metabolic and immune status of metazoans. Their deregulation is associated with age-related pathologies like chronic inflammation and cancer, especially in barrier epithelia. Maintaining a healthy commensal population by preserving innate immun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Linlin, Karpac, Jason, Tran, Susan L., Jasper, Heinrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928474/
https://ncbi.nlm.nih.gov/pubmed/24439372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.12.018
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