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Induction of Atrial Fibrillation by Neutrophils Critically Depends on CD11b/CD18 Integrins

BACKGROUND: Recent observational clinical and ex-vivo studies suggest that inflammation and in particular leukocyte activation predisposes to atrial fibrillation (AF). However, whether local binding and extravasation of leukocytes into atrial myocardium is an essential prerequisite for the initiatio...

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Detalhes bibliográficos
Main Authors: Friedrichs, Kai, Adam, Matti, Remane, Lisa, Mollenhauer, Martin, Rudolph, Volker, Rudolph, Tanja K., Andrié, René P., Stöckigt, Florian, Schrickel, Jan W., Ravekes, Thorben, Deuschl, Florian, Nickenig, Georg, Willems, Stephan, Baldus, Stephan, Klinke, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928425/
https://ncbi.nlm.nih.gov/pubmed/24558493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089307
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