Thiol/Redox Metabolomic Profiling Implicates GSH Dysregulation in Early Experimental Graft versus Host Disease (GVHD)

Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this report, thiol/redox metabolomics was used to identify metabolic perturbation...

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Détails bibliographiques
Auteurs principaux: Suh, Jung H., Kanathezhath, Bindu, Shenvi, Swapna, Guo, Hua, Zhou, Alicia, Tiwana, Anureet, Kuypers, Frans, Ames, Bruce N., Walters, Mark C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928313/
https://ncbi.nlm.nih.gov/pubmed/24558439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088868
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