Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4(+) T Cells

BACKGROUND: Many HIV-2 and SIV isolates, as well as some HIV-1 strains, can use the orphan 7-transmembrane receptor GPR15 as co-receptor for efficient entry into host cells. GPR15 is expressed on central memory and effector memory CD4(+) T cells in healthy individuals and a subset of these cells is...

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Detalhes bibliográficos
Main Authors: Kiene, Miriam, Rethi, Bence, Jansson, Marianne, Dillon, Stephanie, Lee, Eric, Lantto, Rebecka, Wilson, Cara, Pöhlmann, Stefan, Chiodi, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928197/
https://ncbi.nlm.nih.gov/pubmed/24558379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088195
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