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Pharmacokinetics and pharmacodynamics of turoctocog alfa and N8-GP in haemophilia A dogs

The objective of the present study was to evaluate the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the new recombinant FVIII compound turoctocog alfa and a Glyco-PEGylated FVIII derivative thereof (N8-GP) in Haemophilia A dogs. Six haemophilic dogs divided into two groups were included...

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Autores principales: AGERSØ, H., STENNICKE, H. R., PELZER, H., OLSEN, E. N., MERRICKS, E. P., DEFRIESS, N. A., NICHOLS, T. C., EZBAN, M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928143/
https://ncbi.nlm.nih.gov/pubmed/22812621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2516.2012.02896.x
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