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Molecular Dynamics Simulations of the Cardiac Troponin Complex Performed with FRET Distances as Restraints

Cardiac troponin (cTn) is the Ca(2+)-sensitive molecular switch that controls cardiac muscle activation and relaxation. However, the molecular detail of the switching mechanism and how the Ca(2+) signal received at cardiac troponin C (cTnC) is communicated to cardiac troponin I (cTnI) are still elus...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jayasundar, Jayant James, Xing, Jun, Robinson, John M., Cheung, Herbert C., Dong, Wen-Ji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928104/
https://ncbi.nlm.nih.gov/pubmed/24558365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087135
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