Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway.
The orphan nuclear receptor Nur77/N10 has recently been demonstrated to be involved in apoptosis of T cell hybridomas. We report here that chronic expression of Nur77/N10 in thymocytes of transgenic mice results in a dramatic reduction of CD4+CD8+ double-positive as well as CD4+CD8- and CD4-CD8+ sin...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.11.5533 |
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