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Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment

In vivo, antibiotics are often much less efficient than ex vivo and relapses can occur. The reasons for poor in vivo activity are still not completely understood. We have studied the fluoroquinolone antibiotic ciprofloxacin in an animal model for complicated Salmonellosis. High-dose ciprofloxacin tr...

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Autors principals: Kaiser, Patrick, Regoes, Roland R., Dolowschiak, Tamas, Wotzka, Sandra Y., Lengefeld, Jette, Slack, Emma, Grant, Andrew J., Ackermann, Martin, Hardt, Wolf-Dietrich
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928039/
https://ncbi.nlm.nih.gov/pubmed/24558351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001793
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