Immunostimulatory Oligonucleotides Attenuate Airways Remodeling in Allergic Monkeys

To determine whether inhaled immunostimulatory DNA sequence oligonucleotides containing CpG motifs mitigate the pathophysiologic manifestation of the asthmatic phenotype (airways hyperresponsiveness and airways remodeling), rhesus monkeys with experimentally induced allergic airways disease were tre...

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Bibliografiske detaljer
Main Authors: Fanucchi, Michelle V., Schelegle, Edward S., Baker, Gregory L., Evans, Michael J., McDonald, Ruth J., Gershwin, Laurel J., Raz, Eyal, Hyde, Dallas M., Plopper, Charles G., Miller, Lisa A.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927836/
https://ncbi.nlm.nih.gov/pubmed/15306532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200404-533OC
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