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Isolation and characterization of mutants of human diploid fibroblasts resistant to diphtheria toxin.

Stable mutants highly resistant to the protein synthesis inhibitor diphtheria toxin (dipr) have been selected in human diploid fibroblast cells at a frequency of 1-8 X 10(-6). Treatment of cells with mutagens, (e.g., ethylmethanesulfonate, nitrosoguanidine, and ICR-170), increased the frequencies of...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gupta, R S, Siminovitch, L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277932/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3337
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