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Remodeling of Fumagillol: Discovery of an Oxygen-Directed Oxidative Mannich Reaction
[Image: see text] An efficient, two-step construction of highly complex alkaloid-like compounds from the natural product fumagillol is described. This approach, which mimics a biosynthetic cyclase/oxidase sequence, allows for rapid and efficient structure elaboration of the basic fumagillol scaffold...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3927640/ https://ncbi.nlm.nih.gov/pubmed/24410175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4035269 |
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