The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
The ob gene product, leptin, apparently exclusively expressed in adipose tissue, is a signaling factor regulating body weight homeostasis and energy balance. ob gene expression is increased in obese rodents and regulated by feeding, insulin, and glucocorticoids, which supports the concept that ob ge...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.11.5507 |
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