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Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.

The thermodynamic parameters, deltaG, deltaH, and deltaS characterizing the tight binding of methotrexate, folates, and pyridine nucleotides to chicken liver dihydrofolate reductase (5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, EC 1.5.1.3) have been determined from calorimetric and fluorescence m...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Subramanian, S, Kaufman, B T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1978
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392742/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/28523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3201
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