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High-resolution mapping of the spatial organization of a bacterial chromosome

Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of Hi-C to map the structure of bacterial chromosomes. Analysis of Hi-C data and polymer modeling indicates that the Caulobacter crescentus chromosome consis...

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Detalhes bibliográficos
Main Authors: Le, Tung B.K., Imakaev, Maxim V., Mirny, Leonid A., Laub, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927313/
https://ncbi.nlm.nih.gov/pubmed/24158908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1242059
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