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Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity.

Specific targeting of the recombinant, Ca2+ -sensitive photoprotein, aequorin to intracellular organelles has provided new insights into the mechanisms of intracellular Ca2+ homeostasis. When applied to small mammalian cells, a major limitation of this technique has been the need to average the sign...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Rutter, G A, Burnett, P, Rizzuto, R, Brini, M, Murgia, M, Pozzan, T, Tavaré, J M, Denton, R M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.11.5489
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