A novel role of EMMPRIN/CD147 in transformation of quiescent fibroblasts to cancer-associated fibroblasts by breast cancer cells

We tested the novel hypothesis that EMMPRIN/CD147, a transmembrane glycoprotein overexpressed in breast cancer cells, has a previously unknown role in transforming fibroblasts to cancer-associated fibroblasts, and that cancer-associated fibroblasts in turn induce epithelial-to-mesenchymal transition...

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Huvudupphovsmän: Xu, Jing, Lu, Yang, Qiu, Songbo, Chen, Zhi-Nan, Fan, Zhen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927232/
https://ncbi.nlm.nih.gov/pubmed/23474495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.054
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