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ATP-induced conformational changes in the restriction endonuclease from Escherichia coli K-12.

ATP induces a conformational change in the Escherichia coli K-12 restriction enzyme that allows it to discriminate between unmodified and modified DNA recognition sequences. This conformational change does not require ATP hydrolysis. However, ATP hydrolysis is a requirement for DNA cleavage.

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Bibliografische gegevens
Hoofdauteurs: Bickle, T A, Brack, C, Yuan, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1978
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC392721/
https://ncbi.nlm.nih.gov/pubmed/356045
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