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Genotoxic mixtures and dissimilar action: concepts for prediction and assessment

Combinations of genotoxic agents have frequently been assessed without clear assumptions regarding their expected (additive) mixture effects, often leading to claims of synergisms that might in fact be compatible with additivity. We have shown earlier that the combined effects of chemicals, which in...

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Hlavní autoři: Ermler, Sibylle, Scholze, Martin, Kortenkamp, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927065/
https://ncbi.nlm.nih.gov/pubmed/24297155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-013-1170-x
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