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PIP(3)-dependent macropinocytosis is incompatible with chemotaxis

In eukaryotic chemotaxis, the mechanisms connecting external signals to the motile apparatus remain unclear. The role of the lipid phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) has been particularly controversial. PIP(3) has many cellular roles, notably in growth control and macropinocytosis as...

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Détails bibliographiques
Auteurs principaux: Veltman, Douwe M., Lemieux, Michael G., Knecht, David A., Insall, Robert H.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926956/
https://ncbi.nlm.nih.gov/pubmed/24535823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201309081
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