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Familial CRC—Beyond the Lynch Syndrome

Although 30% of individuals diagnosed with CRC report a family history of the disease, only 5–6% carry germline mutations in genes associated with known hereditary cancer syndromes. The evaluation and management of families affected with CRC can be complicated by variability in disease phenotypes an...

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Bibliographic Details
Main Authors: Stoffel, Elena M., Kastrinos, Fay
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926911/
https://ncbi.nlm.nih.gov/pubmed/23962553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2013.08.015
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