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Regulation of Adrenocortical Steroid Hormone Production by RhoA-Diaphanous 1 Signaling and the Cytoskeleton

The production of glucocorticoids and aldosterone in the adrenal cortex is regulated at multiple levels. Biosynthesis of these hormones is initiated when cholesterol, the substrate, enters the inner mitochondrial membrane for conversion to pregnenolone. Unlike most metabolic pathways, the biosynthes...

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Detalhes bibliográficos
Main Authors: Sewer, Marion B., Li, Donghui
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926866/
https://ncbi.nlm.nih.gov/pubmed/23186810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.11.014
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