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N-terminus regulation of VMAT2 mediates methamphetamine stimulated efflux

The 20 amino acid N-terminus of the vesicular monoamine transporter 2 (VMAT2) was examined as a regulator of VMAT2 function. Removal of the first 16 or 19 amino acids of the N-terminus resulted in a molecule with reduced ability to sequester [(3)H]-5HT. A GST-construct of the N-terminus underwent ph...

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Détails bibliographiques
Auteurs principaux: Torres, Brian, Ruoho, Arnold E.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926813/
https://ncbi.nlm.nih.gov/pubmed/24321511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.11.059
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