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Diabetic cataract formation: potential role of glycosylation of lens crystallins.

A high glucose concentration in vivo or an increased glucose of glucose 6-phosphate concentration in vitro has been found to lead to the glycosylation of epsilon-amino groups of lysine residues in bovine and rat lens crystallins. In vitro, this glycosylation imparts an increased susceptibility of th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Stevens, V J, Rouzer, C A, Monnier, V M, Cerami, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392677/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2918
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