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Novel application of digital microfluidics for the detection of biotinidase deficiency in newborns

OBJECTIVE: Newborn screening for biotinidase deficiency can be performed using a fluorometric enzyme assay on dried blood spot specimens. As a pre-requisite to the consolidation of different enzymatic assays onto a single platform, we describe here a novel analytical method for detecting biotinidase...

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Detalhes bibliográficos
Main Authors: Graham, Carrie, Sista, Ramakrishna S, Kleinert, Jairus, Wu, Ning, Eckhardt, Allen, Bali, Deeksha, Millington, David S, Pamula, Vamsee K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926755/
https://ncbi.nlm.nih.gov/pubmed/24036022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinbiochem.2013.09.003
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