Analysis of the B-RAF(V600E) mutation in cutaneous melanoma patients with occupational sun exposure

Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including B-RAF mutation. It has been hypothesized that B-RAF mutations in melanocytic l...

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Main Authors: CANDIDO, SAVERIO, RAPISARDA, VENERANDO, MARCONI, ANDREA, MALAPONTE, GRAZIA, BEVELACQUA, VALENTINA, GANGEMI, PIETRO, SCALISI, AURORA, McCUBREY, JAMES A., MAESTRO, ROBERTA, SPANDIDOS, DEMETRIOS A., FENGA, CONCETTINA, LIBRA, MASSIMO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926654/
https://ncbi.nlm.nih.gov/pubmed/24424406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.2977
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