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Liver cell-mediated mutagenesis of mammalian cells by liver carcinogens.

A cell-mediated mutagenesis assay using primary cultures of rat liver cells and V79 Chinese hamster cells has been developed. Liver carcinogens and their structural analogues were studied. Mutations in the V79 cells were characterized by resistance to ouabain. Cocultivation of the liver cells and V7...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Langenbach, R, Freed, H J, Huberman, E
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1978
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/149308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2864
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