Neuropilin-2 is upregulated in lung cancer cells during TGFβ1-induced epithelial-mesenchymal transition

The epithelial-mesenchymal transition (EMT) and its reversal, MET, are fundamental processes involved in tumor cell invasion and metastasis. SEMA3F is a secreted semaphorin and tumor suppressor downregulated by TGFβ1 and ZEB1-induced EMT. Here we report that NRP2, the high-affinity receptor for SEMA...

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Main Authors: Nasarre, Patrick, Gemmill, Robert M., Potiron, Vincent A., Roche, Joëlle, Lu, Xian, Barón, Anna E., Korch, Christopher, Garrett-Mayer, Elizabeth, Lagana, Alessandro, Howe, Philip H., Drabkin, Harry A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926507/
https://ncbi.nlm.nih.gov/pubmed/24121493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1755
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