Genetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor

BACKGROUND & AIMS: Increasing grade of pancreatic intraepithelial neoplasia (PanIN) has been associated with progression to pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms that control progression from PanINs to PDAC are not well understood. We investigated the genetic alteratio...

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Auteurs principaux: Murphy, Stephen J., Hart, Steven N., Lima, Joema Felipe, Kipp, Benjamin R., Klebig, Mitchell, Winters, Jennifer L, Szabo, Csilla, Zhang, Lizhi, Eckloff, Bruce W., Petersen, Gloria M., Scherer, Steven E., Gibbs, Richard A., McWilliams, Robert R., Vasmatzis, George, Couch, Fergus J.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926442/
https://ncbi.nlm.nih.gov/pubmed/23912084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.049
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