Relationship between 17-alpha hydroxyprogesterone caproate concentration and spontaneous preterm birth

OBJECTIVE: 17-alpha hydroxyprogesterone caproate (17-OHPC) 250 mg weekly reduces recurrent spontaneous preterm birth (SPTB) in women with a prior SPTB by 33%. The dose is not based on pharmacological considerations. A therapeutic concentration has not been determined hampering any attempt to optimiz...

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Main Authors: CARITIS, Steve N., VENKATARAMANAN, Raman, THOM, Elizabeth, HARPER, Margaret, KLEBANOFF, Mark A., SOROKIN, Yoram, THORP, John M., VARNER, Michael W., WAPNER, Ronald J, IAMS, Jay D., CARPENTER, Marshall W., Grobman, William A., MERCER, Brian M., SCISCIONE, Anthony, ROUSE, Dwight J., RAMIN, Susan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926421/
https://ncbi.nlm.nih.gov/pubmed/24113254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2013.10.008
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