Relationship between 17-alpha hydroxyprogesterone caproate concentration and spontaneous preterm birth

OBJECTIVE: 17-alpha hydroxyprogesterone caproate (17-OHPC) 250 mg weekly reduces recurrent spontaneous preterm birth (SPTB) in women with a prior SPTB by 33%. The dose is not based on pharmacological considerations. A therapeutic concentration has not been determined hampering any attempt to optimiz...

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Huvudupphovsmän: CARITIS, Steve N., VENKATARAMANAN, Raman, THOM, Elizabeth, HARPER, Margaret, KLEBANOFF, Mark A., SOROKIN, Yoram, THORP, John M., VARNER, Michael W., WAPNER, Ronald J, IAMS, Jay D., CARPENTER, Marshall W., Grobman, William A., MERCER, Brian M., SCISCIONE, Anthony, ROUSE, Dwight J., RAMIN, Susan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926421/
https://ncbi.nlm.nih.gov/pubmed/24113254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2013.10.008
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